Hypertrophic osteopathy secondary to gastric squamous cell carcinoma in a horse

Hypertrophic osteopathy (Marie’s disease) is a syndrome characterised by periosteal proliferation along the metaphyses and diaphyses proximal and distal to the joints of long bones classically associated with space-occupying lesions of the thorax (Butler et al. 1993). The syndrome is most frequently documented in human and canine patients (Brown et al. 1980), but has also been diagnosed infrequently in the cat (Nafe et al. 1981), cattle, sheep (Smith et al. 1972), deer (Brown et al. 1980), alpaca (Curtis et al. 1997) and horse (Mair et al. 1996). Only recently has hypertrophic osteopathy been documented secondary to extrathoracic lesions in the horse (Sweeney et al. 1989; Lavoie et al. 1992; Mair et al. 1996; van der Kolk et al. 1998). This is the first known published record of hypertrophic osteopathy secondary to gastric squamous cell carcinoma in the horse.